The Role of Marula Oil in Alleviating Photoaging: Insights into its Bioactive Components
Keywords:
Marula oil, anti-aging, skin-aging, photoaging
Abstract
Photoaging, caused by prolonged UV exposure, accelerates skin aging through oxidative stress, collagen degradation, and inflammation. With growing consumer demand for natural and sustainable anti-aging solutions, marula oil has gained attention for its potential in mitigating photoaging. Derived from Sclerocarya birrea, marula oil is rich in fatty acids (oleic and palmitic acids) and antioxidants like vitamin C and E. This review investigates marula oil’s bioactive components and their mechanisms of action in alleviating photoaging, focusing on its moisturizing, antioxidant, and photoprotective properties. Moreover, clinical studies examine its ability to improve skin hydration, enhance barrier function, and inhibit enzymes associated with collagen degradation. Despite its promise as a cosmeceutical, long-term studies are necessary to explore its sustained efficacy, molecular pathways, and potential synergy with other natural ingredients.
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References
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Khalid, A., Iqbal, Z., Rehman, S.-U., & Yousaf, Z. (2024). Role of vitamin C in skin aging mechanism-a narrative review. Journal of Health and Rehabilitation Research, 4(2), 1489–1494. https://doi.org/10.61919/jhrr.v4i2.1078
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Komane, B., Vermaak, I., Summers, B., & Viljoen, A. (2015). Safety and efficacy of Sclerocarya birrea (A.Rich.) Hochst (marula) oil: A clinical perspective. Journal of Ethnopharmacology, 176, 327–335. https://doi.org/10.1016/j.jep.2015.10.037
Krutmann, J., Schalka, S., Watson, R. E. B., Wei, L., & Morita, A. (2021). Daily photoprotection to prevent photoaging. Photodermatology, Photoimmunology & Photomedicine, 37(6), 482–489. https://doi.org/10.1111/phpp.12688
Lee, S., Yu, J. S., Phung, H. M., Lee, J. G., Kim, K. H., & Kang, K. S. (2020). Potential anti-skin aging effect of (-)-catechin isolated from the root bark of ulmus davidiana var. japonica in tumor necrosis factor-α-stimulated normal human dermal fibroblasts. Antioxidants, 9(10), 981. https://doi.org/10.3390/antiox9100981
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Mariod, A. A., & Abdelwahab, S. I. (2012). Sclerocarya birrea(Marula), An African Tree of Nutritional and Medicinal Uses: A Review. Food Reviews International, 28(4), 375–388. https://doi.org/10.1080/87559129.2012.660716
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Mercurio, D. G., Wagemaker, T. A. L., Alves, V. M., Benevenuto, C. G., Gaspar, L. R., & Maia Campos, P. M. B. G. (2015). In vivo photoprotective effects of cosmetic formulations containing UV filters, vitamins, ginkgo biloba and red algae extracts. Journal of Photochemistry and Photobiology B: Biology, 153, 121–126. https://doi.org/10.1016/j.jphotobiol.2015.09.016
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Naidoo, K., Hanna, R., & Birch-Machin, M. A. (2017). What is the role of mitochondrial dysfunction in skin photoaging? Experimental Dermatology, 27(2), 124–128. https://doi.org/10.1111/exd.13476
Niki, E., & Noguchi, N. (2021). Antioxidant action of vitamin E in vivo as assessed from its reaction products with multiple biological oxidants. Free Radical Research, 1–12. https://doi.org/10.1080/10715762.2020.1866181
Ojha, P. K., Poudel, D. K., Rokaya, A., Maharjan, S., Timsina, S., Poudel, A., Satyal, R., Satyal, P., & Setzer, W. N. (2024). Chemical Compositions and Essential Fatty Acid Analysis of Selected Vegetable Oils and Fats. Compounds, 4(1), 37–70. https://doi.org/10.3390/compounds4010003
Park, H. J., Byun, K.-A., Oh, S., Kim, H. M., Chung, M. S., Son, K. H., & Byun, K. (2022). The combination of niacinamide, vitamin C, and PDRN mitigates melanogenesis by modulating nicotinamide nucleotide transhydrogenase. Molecules, 27(15), 4923. https://doi.org/10.3390/molecules27154923
Pegoraro, N. S., Barbieri, A. V., Camponogara, C., Mattiazzi, J., Brum, E. S., Marchiori, M. C. L., Oliveira, S. M., & Cruz, L. (2017). Nanoencapsulation of coenzyme Q10 and vitamin E acetate protects against UVB radiation-induced skin injury in mice. Colloids and Surfaces B: Biointerfaces, 150, 32–40. https://doi.org/10.1016/j.colsurfb.2016.11.013
Pratiwi, K. D., Listiawan, M. Y., Ervianti, E., Sigit, R., Damayanti, D., Hendradi, E., & Sawitri, S. (2021). The efficacy of topical vitamin C and microneedling for photoaging. Berkala Ilmu Kesehatan Kulit Dan Kelamin/Berkala Ilmu Kesehatan Kulit Dan Kelamin (Periodical of Dermatology and Venerology), 33(1), 55–55. https://doi.org/10.20473/bikk.v33.1.2021.55-62
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Published
2025-09-30
How to Cite
Raisinghani, P., Lestari, N., Suyanto, K., & Utama, A. (2025). The Role of Marula Oil in Alleviating Photoaging: Insights into its Bioactive Components. Indonesian Journal of Life Sciences, 7(02), 15-31. https://doi.org/https://doi.org/10.54250/ijls.v7i02.237
Issue
Section
Life Science for Health and Wellbeing
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