The Effects and Treatments for Usher Syndrome: A Review

  • Devita Mayanda Heerlie Institut Bio Scientia Internasional Indonesia, Jakarta, Indonesia
  • Febrina Margaretha Institut Bio Scientia Internasional Indonesia, Jakarta, Indonesia
  • Daniel Ryan Fugaha Institut Bio Scientia Internasional Indonesia, Jakarta, Indonesia
  • Arli Aditya Parikesit Institut Bio Scientia Internasional Indonesia, Jakarta, Indonesia
Keywords: Deaf-blindness, molecular genetics, prevalence, treatment, usher syndrome


Usher syndrome is defined as the rare genetic disorder that affects both vision and auditory. Although the prevalence is really low, only about 4 to 17 per 100,000 people, it is noted to cover at least 50% of deaf-blindness cases. After reviewing the molecular genetics from several papers, there are several causative genes found with the most prevalent being MYO7A, and USH2A that cause USH type 1 and 2 respectively. Furthermore, other literature has found promising treatments that may help to slow down or prevent further degeneration of the syndrome.


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Author Biographies

Devita Mayanda Heerlie, Institut Bio Scientia Internasional Indonesia, Jakarta, Indonesia

Department of Biotechnology, Institut Bio Scientia International Indonesia

Febrina Margaretha, Institut Bio Scientia Internasional Indonesia, Jakarta, Indonesia

Department of Biotechnology, Institut Bio Scientia International Indonesia

Daniel Ryan Fugaha, Institut Bio Scientia Internasional Indonesia, Jakarta, Indonesia

Department of Biotechnology, Institut Bio Scientia International Indonesia

Arli Aditya Parikesit, Institut Bio Scientia Internasional Indonesia, Jakarta, Indonesia

Department of Biotechnology, Institut Bio Scientia International Indonesia


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How to Cite
Heerlie, D., Margaretha, F., Fugaha, D., & Parikesit, A. (2024). The Effects and Treatments for Usher Syndrome: A Review. Indonesian Journal of Life Sciences, 6(01), 68-82.
Life Science for Health and Wellbeing